MARC details
000 -LEADER |
fixed length control field |
02579nam a2200421 i 4500 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
TR-AnTOB |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20230908000939.0 |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
ta |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
171111b xxu||||| mmmm 00| 0 eng d |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
TR-AnTOB |
Language of cataloging |
eng |
Description conventions |
rda |
Transcribing agency |
TR-AnTOB |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
Türkçe |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
Classification number |
TEZ TOBB FBE BMM YL’18 ÖZL |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Özlü, Buşra |
9 (RLIN) |
123271 |
245 10 - TITLE STATEMENT |
Title |
Meme kanseri tedavisinde doksorubisin yüklü melanin nanoparçacıkların kullanımı / |
Statement of responsibility, etc. |
Buşra Özlü. |
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
Place of production, publication, distribution, manufacture |
Ankara : |
Name of producer, publisher, distributor, manufacturer |
TOBB ETÜ Fen Bilimleri Enstitüsü, |
Date of production, publication, distribution, manufacture, or copyright notice |
2018. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
xiv, 45 pages ; |
Dimensions |
29 cm |
336 ## - CONTENT TYPE |
Source |
rdacontent |
Content type code |
txt |
Content type term |
text |
337 ## - MEDIA TYPE |
Source |
rdamedia |
Media type code |
n |
Media type term |
unmediated |
338 ## - CARRIER TYPE |
Source |
rdacarrier |
Carrier type code |
nc |
Carrier type term |
volume |
502 ## - DISSERTATION NOTE |
Dissertation note |
Tez (Yüksek Lisans)--TOBB ETÜ Fen Bilimleri Enstitüsü Ekim 2018 |
520 ## - SUMMARY, ETC. |
Summary, etc. |
2014 yılı verilerine göre, Türkiye'de kadınlarda en sık görülen kanser türü meme kanseridir (43/100000).Tanı konulan her 4 kadın kanserinden 1'i meme kanseridir.Meme kanserinin tedavisi için klinikte kullanılan yöntemler; cerrahi tedavi, kemoterapi, radyoterapi, hormon tedavisi ve hedefe yönelik tedavidir.Doksorubisin, meme kanseri tedavisinde kullanılan en etkili kemoterapi ilaçlarından biridir.Doza bağlı toksisite, ilaca karşı direncin ortaya çıkması ve kanser hücrelerine karşı düşük seçiciliği,doksorubisinin klinikte kullanımını kısıtlamaktadır.Bu dezavantajları ortadan kaldırmaya yönelik yaklaşımların başında nanoteknoloji gelmektedir. |
|
Summary, etc. |
According to 2014 data, breast cancer is the most common cancer in women in Turkey.One out of every 4 women diagnosed with breast cancer.Currently available clinical procedures are surgery, chemotherapy, radiation therapy.Doxorubicin is an efficient chemotherapy drug usually used in breast cancer therapy.Dose dependent toxicity, drug resistance and low selectivity to cancer cells limit the use of doxorubicin in clinical practice.Nanotechnology is the leading approach to eliminate these disadvantages. |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Tezler, Akademik |
Source of heading or term |
etuturkob |
9 (RLIN) |
32546 |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Melanin |
|
Uncontrolled term |
Doksorubisin |
|
Uncontrolled term |
Nanoparçacık |
|
Uncontrolled term |
İlaç taşıyıcı sistemler |
|
Uncontrolled term |
Kontrollü ilaç salımı |
|
Uncontrolled term |
Melanin |
|
Uncontrolled term |
Doxorubicin |
|
Uncontrolled term |
Nanoparticle |
|
Uncontrolled term |
Drug delivery systems |
|
Uncontrolled term |
Controlled drug release |
710 ## - ADDED ENTRY--CORPORATE NAME |
Corporate name or jurisdiction name as entry element |
TOBB Ekonomi ve Teknoloji Üniversitesi. |
Subordinate unit |
Fen Bilimleri Enstitüsü |
9 (RLIN) |
77078 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Uniform Resource Identifier |
<a href="https://tez.yok.gov.tr/">https://tez.yok.gov.tr/</a> |
Materials specified |
Ulusal Tez Merkezi |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Thesis |
Source of classification or shelving scheme |
Other/Generic Classification Scheme |