MARC details
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04777nam a22005895i 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
DE-He213 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20231109085810.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
220709s2022 sz | s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783030976415 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1007/978-3-030-97641-5 |
| Source of number or code |
doi |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
TR-AnTOB |
| Language of cataloging |
eng |
| Transcribing agency |
TR-AnTOB |
| Description conventions |
rda |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
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| Classification number |
WL 300 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MJN |
| Source |
bicssc |
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| Subject category code |
MED056000 |
| Source |
bisacsh |
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|---|
| Subject category code |
MKJ |
| Source |
thema |
| 096 ## - LOCALLY ASSIGNED NLM-TYPE CALL NUMBER (OCLC) |
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| Classification number |
WL300EBK |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
İngilizce |
| 245 10 - TITLE STATEMENT |
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| Title |
Brain Organoids in Research and Therapy |
| Medium |
[electronic resource] : |
| Remainder of title |
Fundamental Ethical and Legal Aspects / |
| Statement of responsibility, etc. |
edited by Hans-Georg Dederer, David Hamburger. |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
1st ed. 2022. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Cham : |
| Name of producer, publisher, distributor, manufacturer |
Springer International Publishing : |
| -- |
Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2022. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 online resource |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Encoding format |
PDF |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Advances in Neuroethics, |
| International Standard Serial Number |
2522-5685 |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Chapter 1) Introductory Remarks -- Part I) Scientific Background -- Chapter 2) Development of Brain Organoids on the Basis of Genome-Edited iPSC-Derived Brain Cells -- Chapter 3) Cell-Based Therapy and Genome Editing in Parkinson's Disease: Quo Vadis -- Part II) The Status Debate -- Chapter 4) Human Cerebral Organoids: Evolving Entities and Their Moral Status -- Chapter 5). Legal perspective: What is, or Should Be, the Legal Status of Brain Organoids? -- Part III) The Informed Consent Challenge -- Chapter 6) Ethical Perspective: Ethics Considerations Regarding Donors’ and Patients’ Consent -- Chapter 7) The Legal Perspective: The Legal Requirements for—and Limits to—the Donor’s and the Patient’s Consent -- Part IV) The Chimera Issue -- Chapter 8) Moral Permissibility of Transplantation of Human Brain Organoids into Animals -- Chapter 9) Transplantation of Human Brain Organoids into Animals - The Legal Issues -- Part V) The Enhancement Conundrum -- Chapter 10) Building a Better Beast: Enhancing the Minds of Animals -- Chapter 11) Legal Arguments in Favour of and Against Neuroenhancement by Means of Brain Organoids -- Part VI) The Harmonization Problem -- Chapter 12) Legal Perspective: A Global Harmonisation of Legal Standards for Brain Organoid Research and Therapy?. . |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
This volume elucidates the pivotal ethical and legal issues arising from the use of brain organoids for research, therapeutic and enhancement purposes. The function of the human brain is still a mystery. Until recently, only post-mortem tissue was available for a structural examination of the brain. Consequently, the examination results could only reflect the state at the end of life. However, in order to better understand the development and function of the human brain, dynamic and functional investigations of different human brain cells are necessary. This is where brain organoids, artificially grown in vitro miniature brains, provide the opportunity for more flexible research scenarios. At the same time, however, the use of brain organoids in research and therapy raises the question of how these new entities are to be treated from an ethical and legal point of view. Against this background, this volume aims at clarifying the normative implications of the use of brain organoids in research and therapy. The ethical reflections on the status of brain organoids, informed consent, human-to-animal chimeras and neuro-enhancement are mirrored by corresponding legal analyses. The ethical and legal assessments are preceded by an introduction to the scientific and medical background of the brain organoid technology. A final chapter will be devoted to the issue of whether international harmonization of normative standards for brain organoid research and therapy is feasible and advisable. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Neurology . |
|
|---|
| Topical term or geographic name entry element |
Neurosciences. |
|
|---|
| Topical term or geographic name entry element |
Medical Ethics. |
|
|---|
| Topical term or geographic name entry element |
Bioethics. |
|
|---|
| Topical term or geographic name entry element |
Medicine |
| General subdivision |
Research. |
|
|---|
| Topical term or geographic name entry element |
Biology |
| General subdivision |
Research. |
|
|---|
| Topical term or geographic name entry element |
Neurology. |
|
|---|
| Topical term or geographic name entry element |
Neuroscience. |
|
|---|
| Topical term or geographic name entry element |
Medical Ethics. |
|
|---|
| Topical term or geographic name entry element |
Bioethics. |
|
|---|
| Topical term or geographic name entry element |
Biomedical Research. |
| 653 #0 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Brain Diseases |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Dederer, Hans-Georg. |
| Relator term |
editor. |
| Relator code |
edt |
| -- |
http://id.loc.gov/vocabulary/relators/edt |
|
|---|
| Personal name |
Hamburger, David. |
| Relator term |
editor. |
| Relator code |
edt |
| -- |
http://id.loc.gov/vocabulary/relators/edt |
| 710 2# - ADDED ENTRY--CORPORATE NAME |
|---|
| Corporate name or jurisdiction name as entry element |
SpringerLink (Online service) |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Advances in Neuroethics, |
| International Standard Serial Number |
2522-5685 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="https://doi.org/10.1007/978-3-030-97641-5">https://doi.org/10.1007/978-3-030-97641-5</a> |
| Materials specified |
Springer eBooks |
| Public note |
Online access link to the resource |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
National Library of Medicine |
| Koha item type |
E-Book |
