TY  - BOOK
AU  - Paganetti,Harald
ED  - Institute of Physics (Great Britain),
TI  - Proton beam therapy
T2  - Physics world discovery,
SN  - 9780750313704
PY  - 2017///]
CY  - Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK)
PB  - IOP Publishing
KW  - Health Physics
KW  - Cancer
KW  - Radiotherapy
KW  - Proton Therapy
KW  - Physics
KW  - bisacsh
KW  - Neoplasms
KW  - radiotherapy
KW  - SCIENCE / Physics / Astrophysics
KW  - bicssc
KW  - Medical physics
KW  - Proton beams
KW  - Therapeutic use
N1  - "Version: 20170101"--Title page verso; IOP science open access books; Introduction -- Why proton beams? -- Technical challenges -- Physics challenges -- Biological challenges -- Clinical challenges -- Outlook; Final-year undergraduates, new PhD students and early-career scientists; Also available in print
N2  - Cancer therapy is a multi-modality approach including surgery, systemic or targeted chemotherapy, radiation (external beam or radionuclide), and immunotherapy. Radiation is typically administered using external beam photon therapy. Proton therapy has been around for more than 60 years but was restricted to research laboratories until the 1990s. Since then clinical proton therapy has been growing rapidly with currently more than 50 facilities worldwide. The interest in proton therapy stems from the physical properties of protons allowing for advanced dose sculpting around the target and sparing of healthy tissue. This review first evaluates the basics of proton therapy physics and technology and then outlines some of the current physical, biological, and clinical challenges. Solving these will ultimately determine whether proton therapy will continue on its path to becoming mainstream
UR  - http://iopscience.iop.org/book/978-0-7503-1370-4
ER  -