The biology of cancer /
Robert A. Weinberg.
- Second edition.
- xx, 876, A:6, G:30, I:28 pages ; illustrations (chiefly color), 29 cm + 1 DVD-ROM (4 3/4 in.) + 1 sheet (18 x 28 cm)
Accompanying DVD-ROM includes: figures in PowerPoint and JPEG formats, supplementary sidebars, mini-lectures, movies, and media guide. Title on accompanying poster: Pathways in human cancer, revised edition.
The biology and genetics of cells and organisms -- The nature of cancer -- Tumor viruses -- Cellular oncogenes -- Growth factors, receptors, and cancer -- Cytoplasmic signaling circuitry programs many of the traits of cancer -- Tumor suppressor genes -- Prb and control of the cell cycle clock -- P53 and apoptosis: master guardian and executioner -- Eternal life : cell immortalization and tumorigenesis -- Multi-step tumorigenesis -- Maintenance of genomic integrity and the development of cancer -- Dialogue replaces monologue : heterotypic interactions and the biology of angiogenesis -- Moving out : invasion and metastasis -- Crowd control : tumor immunology and immunotherapy -- The rational treatment of cancer.
9780815342199 (hardback) 9780815342205 (pbk.)
2013012335
Cancer--Molecular aspects. Cancer--Genetic aspects. Cancer cells.