Clinical trials in older adults /
edited by Antonio Cherubini [and five others].
- 1 online resource
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Includes bibliographical references and index.
The exclusion of older subjects from clinical trials : the predict study / Antonio Cherubini, Peter Crome -- Clinical trials in older adults : a point of view from the industry / Susanna Del Signore, Philippe Guillet -- Ethical issues in clinical trials involving older subjects : the right to participate in clinical trials and have access to care; the protection of vulnerable subjects and the issue of informed consent / Emmanuel Hirsch, Paul-Loup Weil-Dubuc -- Mastering the design of clinical trials for older persons : the tension between external validity and feasibility / Luigi Ferrucci, Stephanie Studenski -- Pharmacokinetic and pharmacodynamic studies in older adults / Arduino A Mangoni, Paul AF Jansen, Stephen H.D. Jackson -- The role of comprehensive geriatric assessment of older adults in clinical studies / Graziano Onder, Agnese Collamati, Andrea Poscia, Roberto Bernabei -- Statistical issues in designing and interpreting clinical trials in older adults / Heather Allore, Mark A. Espeland, Michael E. Miller -- Challenges in implementing large-scale clinical trials in moderately functioning older adults / Stephen D. Anton, Sandrine Sourdet, Marco Pahor, & Todd Manini -- Clinical trials in Alzheimer's disease / Julien Delrieu, Bruno Vellas -- Clinical trials in late-life mood disorders / Lucio Ghio, Werner Natta, Marco Vaggi, Luigi Ferrannini -- Clinical trials for conditions of low muscle mass and strength / Stephanie Studenski, Rosaly Correa-de-Araujo and Luigi Ferrucci -- Clinical trials of cancer treatment in the elderly / Lodovico Balducci, Iordanis Gravanis, Francesco Pignatti -- Clinical trials in nursing homes : challenges and practical solutions / Sandra Simmons, Barbara Resnik, John Schnelle, Joe Ouslander