Ankylosing Spondylitis - Axial Spondyloarthritis [electronic resource] : Cellular, Molecular and Environmental Factors / edited by Mohammad Hossein Nicknam.

Part 1 Introduction -- 1 An overview to Ankylosing spondylitis and Spondyloarthropathies -- Part 2 Cells and cytokines -- 2 Innate Immune-Related Cells and Cytokines in Spondyloarthropathies -- 3 Adaptive Immune-Related Cells and Cytokines in Spondyloarthropathies -- Part 3 -- 4 Association of HLA and HLA Related Genes with Ankylosing Spondylitis -- 5 Association of non-HLA genes with ankylosing spondylitis -- Part 4 -- Environmental factors -- 6 Spondyloarthropathies and Gut microbiota -- 7 Spondyloarthropathies and Food Intake -- 8 Spondyloarthropathies and Environmental Stresses.

Ankylosing Spondylitis is a chronic autoimmune disease that affects about 1-3% of the world population. This debilitating disease affecting primarily young males exerts considerable socio-economic consequences. The exact pathogenesis of AS has not yet been fully understood; therefore, novel, detailed information sources are required. This book offers cutting-edge knowledge about the molecular basic and immunological mechanisms involved in the pathogenesis of Ankylosing Spondylitis. It is one of the scarce scientific resources discussing the environmental factors triggering the disease, along with the clinical manifestations, diagnostic methods, and treatments. This book covers the most recent and reliable researches and developments about spondyloarthropathies in order to provide elaborated, integrated guidance on the molecular mechanisms of Spondyloarthropathies. It will prove helpful for rheumatologists, immunologists, biologists, geneticists, and medical science students who wish to learn more about SpAs.