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008			221112s2022 sz | s |||| 0|eng d
020			_a9783031162589
024	7		_a10.1007/978-3-031-16258-9 _2doi
040			_aTR-AnTOB _beng _cTR-AnTOB _erda
060	0	0	_aWK 550
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072		7	_aMED027000 _2bisacsh
072		7	_aMJG _2thema
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245	1	0	_aAcromegaly _h[electronic resource] : _bA Guide to Diagnosis and Treatment / _cedited by Lewis S. Blevins Jr., Manish K. Aghi.
250			_a1st ed. 2022.
264		1	_aCham : _bSpringer International Publishing : _bImprint: Springer, _c2022.
300			_a1 online resource
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aContemporary Endocrinology, _x2523-3793
505	0		_aThe Molecular Biology and Pathology of Acromegaly -- Growth Hormone-releasing Hormone Secreting Neuroendocrine Tumors -- Diagnosis of Acromegaly -- Imaging in Acromegaly -- The Clinical Presentation of Acromegaly -- Sleep-Disordered Breathing in Acromegaly -- Cardiovascular Pathology in Acromegaly -- Diabetes and Acromegaly -- Musculoskeletal Disorders of Acromegaly -- Acromegaly and Cancer -- Mortality in Acromegaly -- An Overview to the Approach to the Management of Acromegaly -- Transsphenoidal Surgery for Acromegaly -- Stereotactic Radiosurgery and Radiation Therapy for Acromegaly -- Challenging Questions in the Management of Acromegaly in the Young -- Somatostatin Analogues in the Management of patients with Acromegaly -- Use of Dopamine Agonists for Acromegaly -- Pegvisomant: Lessons Learned After 20 Years and Practical Recommendations of its use for the Treatment of Acromegaly -- Perspectives on Combination Medical Therapy in the Treatment of Acromegaly -- Long-term Follow-up of Patients with Acromegaly -- A Patient’s Perspective on Acromegaly.
520			_aReviewing the most current literature, this text is a guide to medical decision-making regarding the diagnosis and treatment of patients with acromegaly. The scope of the book is comprehensive, covering all relevant facets of acromegaly, beginning with a history of the disorder and a review of the somatotrophic axis. Etiology is then discussed, including growth hormone secreting pituitary adenomas and other neuroendocrine tumors. Subsequent chapters present imaging modalities and diagnosis via radiology and clinical findings, as well as comorbid symptoms such as sleep apnea, musculoskeletal considerations, cardiovascular disorders, cancer and diabetes. Both medical and surgical management chapters describe each in detail, including radiotherapy, transsphenoidal surgery, somatostatin analogues and dopamine agonists. Concluding chapters present long-term follow-up as well as an extended selected patient story detailing life with the disease. Bringing together the latest in endocrinologic and neurosurgical evidence and practice, Acromegaly will be the go-to resource for this challenging condition for years to come. .
650		0	_aEndocrinology.
650	1	4	_aEndocrinology.
653		0	_aAcromegaly
700	1		_aBlevins Jr., Lewis S. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aAghi, Manish K. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service)
830		0	_aContemporary Endocrinology, _x2523-3793
856	4	0	_uhttps://doi.org/10.1007/978-3-031-16258-9 _3Springer eBooks _zOnline access link to the resource
942			_2NLM _cEBK
041			_aeng