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020 _a9789811647338
024 7 _a10.1007/978-981-16-4733-8
_2doi
040 _aTR-AnTOB
_beng
_cTR-AnTOB
_erda
060 4 _aWE 727
072 7 _aMNS
_2bicssc
072 7 _aMED065000
_2bisacsh
072 7 _aMNS
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096 _aWE727EBK
245 1 0 _aAnkylosing Spondylitis - Axial Spondyloarthritis
_h[electronic resource] :
_bCellular, Molecular and Environmental Factors /
_cedited by Mohammad Hossein Nicknam.
250 _a1st ed. 2022.
264 1 _aSingapore :
_bSpringer Nature Singapore :
_bImprint: Springer,
_c2022.
300 _a1 online resource
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPart 1 Introduction -- 1 An overview to Ankylosing spondylitis and Spondyloarthropathies -- Part 2 Cells and cytokines -- 2 Innate Immune-Related Cells and Cytokines in Spondyloarthropathies -- 3 Adaptive Immune-Related Cells and Cytokines in Spondyloarthropathies -- Part 3 -- 4 Association of HLA and HLA Related Genes with Ankylosing Spondylitis -- 5 Association of non-HLA genes with ankylosing spondylitis -- Part 4 -- Environmental factors -- 6 Spondyloarthropathies and Gut microbiota -- 7 Spondyloarthropathies and Food Intake -- 8 Spondyloarthropathies and Environmental Stresses.
520 _aAnkylosing Spondylitis is a chronic autoimmune disease that affects about 1-3% of the world population. This debilitating disease affecting primarily young males exerts considerable socio-economic consequences. The exact pathogenesis of AS has not yet been fully understood; therefore, novel, detailed information sources are required. This book offers cutting-edge knowledge about the molecular basic and immunological mechanisms involved in the pathogenesis of Ankylosing Spondylitis. It is one of the scarce scientific resources discussing the environmental factors triggering the disease, along with the clinical manifestations, diagnostic methods, and treatments. This book covers the most recent and reliable researches and developments about spondyloarthropathies in order to provide elaborated, integrated guidance on the molecular mechanisms of Spondyloarthropathies. It will prove helpful for rheumatologists, immunologists, biologists, geneticists, and medical science students who wish to learn more about SpAs.
650 0 _aOrthopedics.
650 0 _aRheumatology.
650 1 4 _aOrthopaedics.
650 2 4 _aRheumatology.
653 0 _aSpondylitis, Ankylosing -- metabolism
653 0 _aSpondylitis, Ankylosing -- etiology
653 0 _aSpondylitis, Ankylosing -- immunology
700 1 _aNicknam, Mohammad Hossein.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
856 4 0 _uhttps://doi.org/10.1007/978-981-16-4733-8
_3Springer eBooks
_zOnline access link to the resource
942 _2NLM
_cEBK
041 _aeng