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020			_a9789811654190
024	7		_a10.1007/978-981-16-5419-0 _2doi
040			_aTR-AnTOB _beng _erda _cTR-AnTOB
041			_aeng
060			_aQU 93
072		7	_aMQW _2bicssc
072		7	_aTEC059000 _2bisacsh
072		7	_aMQW _2thema
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245	1	0	_aGene Delivery _h[electronic resource] / _cedited by Huayu Tian, Xuesi Chen.
250			_a1st ed. 2022.
264		1	_aSingapore : _bSpringer Nature Singapore : _bImprint: Springer, _c2022.
300			_a1 online resource
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aBiomaterial Engineering, _x2523-8817
505	0		_aOverview on gene therapy -- Cationic liposome -- Functionalized peptide dendrimers -- Bioresponsive poly(amido amine)s -- Cationic polyphosphoesters -- Polysaccharide-based gene carriers -- Polypeptide-based gene carriers -- Fluorinated gene carriers -- Target gene delivery systems -- Cationic helical polypeptides -- Cyclic cationic polymers -- Cationic bolaamphiphile -- Chitosan-functionalized gene carriers -- Charge-reversal gene carriers -- Multifunctional envelope-type nanodevice -- Drug and gene co-delivery systems -- Oral delivery of gene therapy -- Gene therapy for brain diseases.
520			_aGene delivery is a promising strategy for the specific treatment of numerous gene-associated human diseases by intentionally altering the gene expression in pathological cells. A successful clinical application of gene-based therapy depends on an efficient gene delivery system. Many efforts have been attempted to improve the safety and efficiency of gene-based therapies. Nanoparticles have been proved to be the most promising vehicles for clinical gene therapy due to their tunable size, shape, surface, and biological behaviors. In this volume, the recent developments of nanoparticles for clinical gene therapy will be identified and summarized.
650		0	_aBiomedical engineering.
650		0	_aBiomaterials.
650		0	_aMedical genetics.
650	1	4	_aBiomedical Engineering and Bioengineering.
650	2	4	_aBiomaterials.
650	2	4	_aMedical Genetics.
653		0	_aBiomaterial engineering
700	1		_aTian, Huayu. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aChen, Xuesi. _eeditor. _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service)
830		0	_aBiomaterial Engineering, _x2523-8817
856	4	0	_uhttps://doi.org/10.1007/978-981-16-5419-0 _3Springer eBooks _zOnline access link to the resource
942			_2NLM _cEBK