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Spaceflight and the Central Nervous System

Clinical and Scientific Aspects

  • Book
  • © 2022

Overview

Editors:
  1. Alex P. Michael

    1. Neurological Surgeon, Mercy Clinic Neurosurgery, Saint Louis, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Christian Otto

    1. Director of Teleoncology, Memorial Sloan Kettering Cancer Center, New York, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Millard F. Reschke

    1. NASA Neuroscience, Johnson Space Center, Houston, USA

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    You can also search for this editor in PubMed   Google Scholar

  4. Alan R. Hargens

    1. Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Includes effects of both short and long duration spaceflight effects

  • Offers theoretical background information and tested laboratory protocols

  • Discusses central nervous system physiology and pathology during spaceflight

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-vii
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  2. History of Spaceflight and the Central Nervous System

    • Alex P. Michael, Millard F. Reschke
    Pages 1-7

  3. Cardiovascular Physiology and Fluid Shifts in Space

    • Aya Hesham Sayed, Alan R. Hargens
    Pages 9-21

  4. Effects of Microgravity and Space Radiation on the Nervous System

    • Vivek Mann, Alamelu Sundaresan, Marie-Francoise J. Doursout, Sundar Devakottai
    Pages 23-31

  5. Cognitive Performance and Neuromapping

    • Stijn Thoolen, Gary Strangman
    Pages 33-54

  6. Spine Biomechanics and Pathology

    • Lucas Brane, Jeannie F. Bailey
    Pages 55-65

  7. Vestibular System

    • Jamie M. Bogle, Ashley Zaleski-King
    Pages 67-85

  8. Intraocular Pressure Considerations

    • Yeni H. Yucel, Neeru Gupta
    Pages 87-105

  9. Central Nervous System Neoplasms in Microgravity

    • Kolaparambil Varghese Lydia Johnson, Alex P. Michael, Terje Saehle
    Pages 107-121

  10. Space Renaissance and Neurodegeneration

    • Davide Marotta, Jana Stoudemire, Twyman Clements, Jeanne F. Loring, Paula Grisanti, Scott A. Noggle et al.
    Pages 123-132

  11. Summary and Future Directions

    • Timothy R. Macaulay
    Pages 133-136

  12. Back Matter

    Pages 137-140
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Keywords

About this book

This book consolidates the current knowledge of how short and long-duration spaceflight affects the anatomy and physiology of the central nervous system. It also incorporates the methodology and constraints of studying the central nervous system in space. 


Chapters detail advances in imaging techniques available to assess intracranial and intraocular pathology as well as translational medicine with an emphasis on brain cancer and neurodegenerative disease in spaceflight. Additionally, the book offers theoretical background information, tested laboratory protocols, and step-by-step methods for reproducible lab experiments to aid neuroscientists and neurobiologists in laboratory testing and experimentation. 


Spaceflight and the Central Nervous System is the first to comprehensively include all aspects of spaceflight-induced changes in the central nervous system. It is an invaluable resource for basic and clinical laboratory trainees and researchers in aerospace medicine and physiology or for those looking to gain specific knowledge in spaceflight neuroscience.

Editors and Affiliations

  • Neurological Surgeon, Mercy Clinic Neurosurgery, Saint Louis, USA

    Alex P. Michael

  • Director of Teleoncology, Memorial Sloan Kettering Cancer Center, New York, USA

    Christian Otto

  • NASA Neuroscience, Johnson Space Center, Houston, USA

    Millard F. Reschke

  • Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, USA

    Alan R. Hargens

About the editors

Alex P. Michael, MD

Neurological Surgeon, Mercy Clinic Neurosurgery




Christian Otto, MD
Director of Teleoncology, Memorial Sloan Kettering Cancer Center
Former Lead Scientist for NASA’s Visual Impairment Intracranial Pressure Risk Group


Alan R. Hargens
Department of Orthopaedic Surgery
University of California
San Diego, CA

Millard F. Reschke

Johnson Space Center

NASA Neuroscience

Houston, TX



Bibliographic Information

  • Book Title: Spaceflight and the Central Nervous System

  • Book Subtitle: Clinical and Scientific Aspects

  • Editors: Alex P. Michael, Christian Otto, Millard F. Reschke, Alan R. Hargens

  • DOI: https://doi.org/10.1007/978-3-031-18440-6

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-031-18439-0Published: 29 December 2022

  • Softcover ISBN: 978-3-031-18442-0Published: 30 December 2023

  • eBook ISBN: 978-3-031-18440-6Published: 28 December 2022

  • Edition Number: 1

  • Number of Pages: VII, 140

  • Number of Illustrations: 7 b/w illustrations, 33 illustrations in colour

  • Topics: Neurology, Aerospace Technology and Astronautics

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